What is an AMC?

An Advance Market Commitment is a promise to children around the world that we will work together to protect them from diseases that currently threaten their lives and cut short their hopes for the future.

Advance Market Commitments (AMCs) are a new approach to public health funding designed to stimulate the development and manufacture of vaccines for developing countries.

Donors commit money to guarantee the price of vaccines once they have been developed, thus creating the potential for a viable future market. Decisions about which diseases to target, criteria for effectiveness, price and long-term availability are made in advance by an independent advisory group.

The donor commitments provide vaccine makers with the incentive they need to invest the considerable sums required to conduct research, train staff and build manufacturing facilities.

As part of the AMC, participating companies also make binding commitments to supply the vaccines at lower and sustainable prices after the donor funds made available for the initial fixed price are used up.

Ultimately, developing country governments are able to budget and plan for immunization programmes, knowing that vaccines will be available in sufficient quantity, at a price they can afford, for the long term.

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